Sclerostin Antikörper (AA 130-210)

Produktnummer ABIN7222960

Der Kaninchen Polyklonal Anti-Sclerostin Antikörper wurde für WB und ELISA validiert. Er ist geeignet, Sclerostin in Proben von Human zu detektieren.

Kurzübersicht für Sclerostin Antikörper (AA 130-210) (ABIN7222960)

Target: Sclerostin (SOST)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Sclerostin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Sclerostin Antikörper

Bindungsspezifität: AA 130-210

Verwendungszweck: Sclerostin Polyclonal Antibody

Spezifität: Sclerostin Polyclonal Antibody detects endogenous levels of Sclerostin protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human Sclerostin at AA range: 130-210

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Sclerostin

Target: Sclerostin (SOST)

Andere Bezeichnung: Sclerostin

Hintergrund: Rabbit Anti-Sclerostin Polyclonal Antibody,SOST, Sclerostin,Sclerostin (SOST) is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in SOST are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of SOST, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.,Sclerostin

Molekulargewicht: observerd band 26kDa

Gen-ID: 50964

UniProt: Q9BQB4