SIK2 Antikörper

Produktnummer ABIN7231366

Der Kaninchen Polyklonal anti-SIK2 Antikörper (ABIN7231366) detektiert spezifisch SIK2 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für SIK2 Antikörper (ABIN7231366)

Target: SIK2 (Salt-Inducible Kinase 2 (SIK2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-SIK2 Antikörper

Verwendungszweck: Rabbit Anti-SIK2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of SIK2 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SIK2 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SIK2

Target: SIK2 (Salt-Inducible Kinase 2 (SIK2))

Andere Bezeichnung: SIK2

Hintergrund: Serine/threonine-protein kinase SIK2, Qin-induced kinase, Salt-inducible kinase 2, SIK-2, Serine/threonine-protein kinase SNF1-like kinase 2SIK2 (Salt Inducible Kinase 2) is a Protein Coding gene. Among its related pathways are Glucagon signaling pathway and Glucose/Energy Metabolism. Phosphorylates Ser-794 of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.

Molekulargewicht: 101kD

Gen-ID: 23235

UniProt: Q9H0K1