S100A12 Antikörper (AA 290-370)

Produktnummer ABIN7229764

Der Kaninchen Polyklonal anti-S100A12 Antikörper wird verwendet zum Nachweis von S100A12 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für S100A12 Antikörper (AA 290-370) (ABIN7229764)

Target: S100A12 (S100 Calcium Binding Protein A12 (S100A12))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser S100A12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-S100A12 Antikörper

Bindungsspezifität: AA 290-370

Verwendungszweck: Rabbit Anti-MRP6 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of MRP6 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MRP6 protein at AA range: 290-370

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu S100A12

Target: S100A12 (S100 Calcium Binding Protein A12 (S100A12))

Andere Bezeichnung: MRP6

Hintergrund: Multidrug resistance-associated protein 6, ATP-binding cassette sub-family C member 6, Anthracycline resistance-associated protein, Multi-specific organic anion transporter E, MOAT-EABCC6 (ATP Binding Cassette Subfamily C Member 6) is a Protein Coding gene. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling. The protein encoded by ABCC6 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in ABCC6 cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for ABCC6.

Molekulargewicht: 165kD

Gen-ID: 368

UniProt: O95255

Pathways: Toll-Like Receptors Cascades, S100 Proteine