RNF6 Antikörper (AA 470-550)

Produktnummer ABIN7231114

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch RNF6 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für RNF6 Antikörper (AA 470-550) (ABIN7231114)

Target: RNF6 (RING Finger Protein 6 (RNF6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RNF6 Antikörper

Bindungsspezifität: AA 470-550

Verwendungszweck: RNF6 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of RNF6 protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human RNF6 protein at AA range: 470-550

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu RNF6

Target: RNF6 (RING Finger Protein 6 (RNF6))

Andere Bezeichnung: RNF6

Hintergrund: Rabbit Anti-RNF6 Polyclonal Antibody,E3 ubiquitin-protein ligase RNF6, RING-type E3 ubiquitin transferase RNF6,RNF6 (Ring Finger Protein 6) is a Protein Coding gene. Diseases associated with RNF6 include Esophageal Cancer and Squamous Cell Carcinoma. Among its related pathways are Class I MHC mediated antigen processing and presentation and Androgen receptor signaling pathway. The protein encoded by RNF6 contains a RING-H2 finger motif. Deletions and mutations in RNF6 were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.,RNF6

Molekulargewicht: observerd band 75kDa

Gen-ID: 6049

UniProt: Q9Y252

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Cell Size