RNF185 Antikörper (AA 121-170)

Produktnummer ABIN7231102

Der Kaninchen Polyklonal anti-RNF185 Antikörper (ABIN7231102) detektiert spezifisch RNF185 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für RNF185 Antikörper (AA 121-170) (ABIN7231102)

Target: RNF185 (Ring Finger Protein 185 (RNF185))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF185 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RNF185 Antikörper

Bindungsspezifität: AA 121-170

Verwendungszweck: Rabbit Anti-RN185 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of RN185 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RN185 protein at AA range: 121-170

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu RNF185

Target: RNF185 (Ring Finger Protein 185 (RNF185))

Andere Bezeichnung: RN185

Hintergrund: E3 ubiquitin-protein ligase RNF185, RING finger protein 185, RING-type E3 ubiquitin transferase RNF185RNF185 (Ring Finger Protein 185) is a Protein Coding gene. Diseases associated with RNF185 include Cystic Fibrosis. Among its related pathways are Protein processing in endoplasmic reticulum and HIV Life Cycle. GO annotations related to this gene include ligase activity. An important paralog of this gene is INPP5J. E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating Lys-63-linked polyubiquitination of BNIP1. Responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD pathway. Preferentially associates with the E2 enzymes UBE2J1 and UBE2J2.

Molekulargewicht: 21kD

Gen-ID: 91445

UniProt: Q96GF1