RNF185 Antikörper (AA 121-170)
Kurzübersicht für RNF185 Antikörper (AA 121-170) (ABIN7231102)
Target
Alle RNF185 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 121-170
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Verwendungszweck
- RN185 Polyclonal Antibody
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Spezifität
- The antibody detects endogenous levels of RN185 protein
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Aufreinigung
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human RN185 protein at AA range: 121-170
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Kommentare
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Primary Antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RNF185 (Ring Finger Protein 185 (RNF185))
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Andere Bezeichnung
- RN185
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Hintergrund
- Rabbit Anti-RN185 Polyclonal Antibody,E3 ubiquitin-protein ligase RNF185, RING finger protein 185, RING-type E3 ubiquitin transferase RNF185,RNF185 (Ring Finger Protein 185) is a Protein Coding gene. Diseases associated with RNF185 include Cystic Fibrosis. Among its related pathways are Protein processing in endoplasmic reticulum and HIV Life Cycle. GO annotations related to this gene include ligase activity. An important paralog of this gene is INPP5J. E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating Lys-63-linked polyubiquitination of BNIP1. Responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD pathway. Preferentially associates with the E2 enzymes UBE2J1 and UBE2J2.,RN185
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Molekulargewicht
- observerd band 21kDa
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Gen-ID
- 91445
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UniProt
- Q96GF1
Target
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