RNF123 Antikörper

Produktnummer ABIN7231098

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RNF123 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für RNF123 Antikörper (ABIN7231098)

Target: RNF123 (Ring Finger Protein 123 (RNF123))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF123 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RNF123 Antikörper

Verwendungszweck: Rabbit Anti-RN123 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of RN123 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RN123 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu RNF123

Target: RNF123 (Ring Finger Protein 123 (RNF123))

Andere Bezeichnung: RN123

Hintergrund: E3 ubiquitin-protein ligase RNF123, Kip1 ubiquitination-promoting complex protein 1, RING finger protein 123, RING-type E3 ubiquitin transferase RNF123The Ring Finger Protein 123 encoded by RNF123 contains a C-terminal RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions, and an N-terminal SPRY domain. This protein displays E3 ubiquitin ligase activity toward the cyclin-dependent kinase inhibitor 1B which is also known as p27 or KIP1. Alternative splicing results in multiple transcript variants. RNF123 (Ring Finger Protein 123) is a Protein Coding gene. Among its related pathways are Deubiquitination and Class I MHC mediated antigen processing and presentation.

Molekulargewicht: 144kD

Gen-ID: 63891

UniProt: Q5XPI4