EMP2 Antikörper (AA 65-167)

Produktnummer ABIN716576

Der Kaninchen Polyklonal Anti-EMP2-Antikörper wurde für WB, ELISA, IF (cc), IF (p), IHC (p) und IHC (fro) validiert. Er ist geeignet, EMP2 in Proben von Ratte zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für EMP2 Antikörper (AA 65-167) (ABIN716576)

Target: EMP2 (Epithelial Membrane Protein 2 (EMP2))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EMP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-EMP2 Antikörper

Bindungsspezifität: AA 65-167

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EMP2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-EMP2 Antikörper (ABIN716576)

Torella, Iaconetti, Tarallo, Marino, Giurato, Veneziano, Aquila, Scalise, Mancuso, Cianflone, Valeriano, Marotta, Tammè, Vicinanza, Sasso, Cozzolino, Torella, Weisz, Indolfi: "miRNA Regulation of the Hyperproliferative Phenotype of Vascular Smooth Muscle Cells in Diabetes." in: Diabetes, Vol. 67, Issue 12, pp. 2554-2568, (2019) (PubMed).

Details zu EMP2

Target: EMP2 (Epithelial Membrane Protein 2 (EMP2))

Andere Bezeichnung: Emp2

Hintergrund:

Synonyms: EMP-2, EMP2, EMP2_HUMAN, Epithelial membrane protein 2, Protein XMP.

Background: EMP-2 is a 167 amino acid multi-pass membrane protein that contains four-transmembrane domains and belongs to the GAS3/PMP22 (growth arrest-specific-3/peripheral myelin protein-22) family. Localized to lipid raft domains in the plasma membrane, EMP-2 regulates the expression of several target proteins and is necessary for blastocyst implantation in the uterine endometrium. Specifically, EMP-2 mediates blastocyst implantation by controlling the cell membrane expression of MHC and glycosylphosphatidylinositol-anchored proteins, as well as Integrins and caveolin-1. In adult tissues, EMP-2 is expressed in heart, lung, ovary and intestine, while fetal expression is highest in kidney, brain and liver. Overexpression of EMP-2 is associated with endometrial adenocarcinoma, suggesting a possible role for EMP-2 in tumorigenesis.

Gen-ID: 2013