Rhotekin Antikörper (AA 80-160)

Produktnummer ABIN7224140

Der Kaninchen Polyklonal Anti-Rhotekin Antikörper wurde für ELISA und IHC (p) validiert. Er ist geeignet, Rhotekin in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für Rhotekin Antikörper (AA 80-160) (ABIN7224140)

Target: Rhotekin (RTKN)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Rhotekin Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Rhotekin Antikörper

Bindungsspezifität: AA 80-160

Verwendungszweck: Rhotekin Polyclonal Antibody

Spezifität: Rhotekin Polyclonal Antibody detects endogenous levels of Rhotekin protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Rhotekin at AA range: 80-160

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Rhotekin

Target: Rhotekin (RTKN)

Andere Bezeichnung: Rhotekin

Hintergrund: Rabbit Anti-Rhotekin Polyclonal Antibody,RTKN, RTKN1, Rhotekin,RTKN (rhotekin) encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.,Rhotekin

Gen-ID: 6242

UniProt: Q9BST9