RhoGEF p115 (AA 140-220) Antikörper

Produktnummer ABIN7216838

Der Kaninchen Polyklonal anti-RhoGEF p115 Antikörper wird verwendet zum Nachweis von RhoGEF p115 in Proben von Human, Maus und Ratte. Er wurde validiert für ELISA, WB und IHC.

Kurzübersicht für RhoGEF p115 (AA 140-220) Antikörper (ABIN7216838)

Target: RhoGEF p115

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails

Bindungsspezifität: AA 140-220

Verwendungszweck: Rabbit Anti-RhoGEF p115 Polyclonal Antibody

Spezifität: RhoGEF p115 Polyclonal Antibody detects endogenous levels of RhoGEF p115 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human RhoGEF p115 at AA range: 140-220

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Antigendetails

Target: RhoGEF p115

Hintergrund: ARHGEF1, Rho guanine nucleotide exchange factor 1, 115 kDa guanine nucleotide exchange factor, p115-RhoGEF, p115RhoGEF, Sub1.5Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The rho guanine nucleotide exchange factor 1 may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.

Molekulargewicht: 105kD

Gen-ID: 9138

UniProt: Q92888