Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RhoBTB1/2 in ELISA, IF, IHC und WB. Es zeigt Reaktivität gegenüber Proben von Human und Maus.
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:5000,Not yet tested in other applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Haltbarkeit
12 months
Target
RhoBTB1/2
Hintergrund
RHOBTB1, KIAA0740, Rho-related BTB domain-containing protein 1, RHOBTB2, DBC2, KIAA0717, Rho-related BTB domain-containing protein 2, Deleted in breast cancer 2 gene protein, p83Rho related BTB domain containing 2 encoded by RHOBTB2 is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene.