ARHGEF2 Antikörper (pSer885)

Produktnummer ABIN7225862

Der Kaninchen Polyklonal anti-ARHGEF2 Antikörper wird verwendet zum Nachweis von ARHGEF2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für ARHGEF2 Antikörper (pSer885) (ABIN7225862)

Target: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-ARHGEF2 Antikörper

Bindungsspezifität: pSer885

Verwendungszweck: Rabbit Anti-Lfc (phospho Ser885) Polyclonal Antibody

Spezifität: Phospho-Lfc (S885) Polyclonal Antibody detects endogenous levels of Lfc protein only when phosphorylated at S885.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Lfc Phospho-Ser885

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ARHGEF2

Target: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Andere Bezeichnung: Lfc

Hintergrund: ARHGEF2, KIAA0651, LFP40, Rho guanine nucleotide exchange factor 2, Guanine nucleotide exchange factor H1, GEF-H1, Microtubule-regulated Rho-GEF, Proliferating cell nucleolar antigen p40Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The protein encoded by ARHGEF2 (Rho/Rac guanine nucleotide exchange factor 2)may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.

Molekulargewicht: 111kD

Gen-ID: 9181

UniProt: Q92974

Pathways: Negative Regulation of intrinsic apoptotic Signaling