ARHGEF12 Antikörper (AA 420-500)

Produktnummer ABIN7220696

Der Kaninchen Polyklonal anti-ARHGEF12 Antikörper (ABIN7220696) detektiert spezifisch ARHGEF12 in ELISA und WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für ARHGEF12 Antikörper (AA 420-500) (ABIN7220696)

Target: ARHGEF12 (rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF12 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-ARHGEF12 Antikörper

Bindungsspezifität: AA 420-500

Verwendungszweck: LARG Polyclonal Antibody

Spezifität: LARG Polyclonal Antibody detects endogenous levels of LARG protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human LARG at AA range: 420-500

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu ARHGEF12

Target: ARHGEF12 (rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12))

Andere Bezeichnung: LARG

Hintergrund: Rabbit Anti-LARG Polyclonal Antibody,ARHGEF12, KIAA0382, LARG, Rho guanine nucleotide exchange factor 12, Leukemia-associated RhoGEF,Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The Rho guanine nucleotide exchange factor 12 may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene.,Rho guanine nucleotide exchange factor 12

Molekulargewicht: observerd band 173kDa

Gen-ID: 23365

UniProt: Q9NZN5

Pathways: Neurotrophin Signalübertragung, Regulation of G-Protein Coupled Receptor Protein Signaling