Retinoic Acid Receptor gamma Antikörper (AA 360-440)

Produktnummer ABIN7230942

Der Kaninchen Polyklonal anti-Retinoic Acid Receptor gamma Antikörper wird verwendet zum Nachweis von Retinoic Acid Receptor gamma in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für Retinoic Acid Receptor gamma Antikörper (AA 360-440) (ABIN7230942)

Target: Retinoic Acid Receptor gamma (RARG) (Retinoic Acid Receptor, gamma (RARG))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Retinoic Acid Receptor gamma Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Retinoic Acid Receptor gamma Antikörper

Bindungsspezifität: AA 360-440

Verwendungszweck: Rabbit Anti-RARG Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of RARG protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RARG protein at AA range: 360-440

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Retinoic Acid Receptor gamma

Target: Retinoic Acid Receptor gamma (RARG) (Retinoic Acid Receptor, gamma (RARG))

Andere Bezeichnung: RARG

Hintergrund: Nuclear receptor subfamily 1 group B member 3RARG encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for RARG.

Molekulargewicht: 49kD

Gen-ID: 5916

UniProt: P13631

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Cell Size