RBBP6 Antikörper (AA 270-350)

Produktnummer ABIN7230968

Der Kaninchen Polyklonal anti-RBBP6 Antikörper (ABIN7230968) detektiert spezifisch RBBP6 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für RBBP6 Antikörper (AA 270-350) (ABIN7230968)

Target: RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBBP6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RBBP6 Antikörper

Bindungsspezifität: AA 270-350

Verwendungszweck: Rabbit Anti-RBBP6 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of RBBP6 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RBBP6 protein at AA range: 270-350

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu RBBP6

Target: RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))

Andere Bezeichnung: RBBP6

Hintergrund: E3 ubiquitin-protein ligase RBBP6, Proliferation potential-related protein, Protein P2P-R, RING-type E3 ubiquitin transferase RBBP6, Retinoblastoma-binding Q protein 1, RBQ-1, Retinoblastoma-binding protein 6, p53-associated cellular protein of testisThe retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. RBBP6 (RB Binding Protein 6, Ubiquitin Ligase) encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for RBBP6.

Molekulargewicht: 197kD

Gen-ID: 5930

UniProt: Q7Z6E9

Pathways: Regulatorische RNA Pathways