RCC2 Antikörper (AA 450-530)

Produktnummer ABIN7223586

Der Kaninchen Polyklonal anti-RCC2 Antikörper wird verwendet zum Nachweis von RCC2 in Proben von Human und Maus. Er wurde validiert für WB, ELISA und IHC (p).

Kurzübersicht für RCC2 Antikörper (AA 450-530) (ABIN7223586)

Target: RCC2 (Regulator of Chromosome Condensation 2 (RCC2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RCC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-RCC2 Antikörper

Bindungsspezifität: AA 450-530

Verwendungszweck: RCC2 Polyclonal Antibody

Spezifität: RCC2 Polyclonal Antibody detects endogenous levels of RCC2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human RCC2 at AA range: 450-530

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu RCC2

Target: RCC2 (Regulator of Chromosome Condensation 2 (RCC2))

Andere Bezeichnung: RCC2

Hintergrund: Rabbit Anti-RCC2 Polyclonal Antibody,RCC2, KIAA1470, TD60, Protein RCC2, RCC1-like protein TD-60, Telophase disk protein of 60 kDa,RCC2/TD-60 is a member of the RCC1 (regulator of chromosome condensation 1) family of guanine nucleotide exchange factors. RCC2/TD-60 is associated with the chromosome passenger complex (CPC), which also consists of aurora B kinase, borealin, INCENP (inner centromere protein) and survivin. The CPC acts at various stages of mitosis, interacts with microtubules and is required for proper chromosome segregation and cytokinesis. Regulation of aurora B kinase is key in the regulation of the CPC. In late mitosis, RCC2/TD-60 is required for spindle assembly and recruitment of survivin and aurora B. RCC2/TD-60 is also required for aurora B activation in vitro and localization of the CPC to centromeres.,Protein RCC2

Molekulargewicht: observerd band 56kDa

Gen-ID: 55920

UniProt: Q9P258