RASA4 Antikörper (AA 100-180)

Produktnummer ABIN7230954

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RASA4 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für RASA4 Antikörper (AA 100-180) (ABIN7230954)

Target: RASA4 (RAS P21 Protein Activator 4 (RASA4))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RASA4 Antikörper

Bindungsspezifität: AA 100-180

Verwendungszweck: Rabbit Anti-RASL2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of RASL2 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RASL2 protein at AA range: 100-180

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu RASA4

Target: RASA4 (RAS P21 Protein Activator 4 (RASA4))

Andere Bezeichnung: RASL2

Hintergrund: Ras GTPase-activating protein 4, Calcium-promoted Ras inactivator, Ras p21 protein activator 4, RasGAP-activating-like protein 2RASA4 (RAS P21 Protein Activator 4) encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for RASA4.

Molekulargewicht: 88kD

Gen-ID: 10156

UniProt: O43374