RHOH Antikörper (AA 110-190)

Produktnummer ABIN7222226

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RHOH in WB, ELISA, IF und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für RHOH Antikörper (AA 110-190) (ABIN7222226)

Target: RHOH (Ras Homolog Family Member H (RHOH))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RHOH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Produktdetails anti-RHOH Antikörper

Bindungsspezifität: AA 110-190

Verwendungszweck: Rabbit Anti-Rho H Polyclonal Antibody

Spezifität: Rho H Polyclonal Antibody detects endogenous levels of Rho H protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human Rho H at AA range: 110-190

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu RHOH

Target: RHOH (Ras Homolog Family Member H (RHOH))

Andere Bezeichnung: Rho H

Hintergrund: RHOH, ARHH, TTF, Rho-related GTP-binding protein RhoH, GTP-binding protein TTF, Translocation three four proteinThe protein encoded by RHOH is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. RHOH may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein.

Molekulargewicht: 21kD

Gen-ID: 399

UniProt: Q15669