RASGRP3 Antikörper (AA 90-170)

Produktnummer ABIN7228802

Der Kaninchen Polyklonal anti-RASGRP3 Antikörper (ABIN7228802) detektiert spezifisch RASGRP3 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für RASGRP3 Antikörper (AA 90-170) (ABIN7228802)

Target: RASGRP3 (RAS Guanyl Releasing Protein 3 (Calcium and DAG-Regulated) (RASGRP3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASGRP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RASGRP3 Antikörper

Bindungsspezifität: AA 90-170

Verwendungszweck: Rabbit Anti-GRP3 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of GRP3 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human GRP3 protein at AA range: 90-170

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu RASGRP3

Target: RASGRP3 (RAS Guanyl Releasing Protein 3 (Calcium and DAG-Regulated) (RASGRP3))

Andere Bezeichnung: GRP3

Hintergrund: Ras guanyl-releasing protein 3, Calcium and DAG-regulated guanine nucleotide exchange factor III, Guanine nucleotide exchange factor for Rap1RASGRP3 (RAS Guanyl Releasing Protein 3) is a Protein Coding gene. Among its related pathways are RET signaling and G-protein signaling TC21 regulation pathway. GO annotations related to RASGRP3 include calcium ion binding and GTPase activator activity. The protein encoded by RASGRP3 is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in RASGRP3 have been associated with systemic lupus erythematosus and several cancers.

Molekulargewicht: 75kD

Gen-ID: 25780

UniProt: Q8IV61