RORB Antikörper (AA 210-290)

Produktnummer ABIN7231126

Der Kaninchen Polyklonal anti-RORB Antikörper wird verwendet zum Nachweis von RORB in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für RORB Antikörper (AA 210-290) (ABIN7231126)

Target: RORB (RAR-Related Orphan Receptor B (RORB))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RORB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RORB Antikörper

Bindungsspezifität: AA 210-290

Verwendungszweck: Rabbit Anti-RORB Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of RORB protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RORB protein at AA range: 210-290

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu RORB

Target: RORB (RAR-Related Orphan Receptor B (RORB))

Andere Bezeichnung: RORB

Hintergrund: Nuclear receptor ROR-beta, Nuclear receptor RZR-beta, Nuclear receptor subfamily 1 group F member 2, Retinoid-related orphan receptor-betaThe protein encoded by RORB (RAR Related Orphan Receptor B) is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, and to help regulate the expression of some genes involved in circadian rhythm.

Molekulargewicht: 51kD

Gen-ID: 6096

UniProt: Q92753

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway