RAB3IP Antikörper (AA 230-310)

Produktnummer ABIN7219372

Der Kaninchen Polyklonal anti-RAB3IP Antikörper wird verwendet zum Nachweis von RAB3IP in Proben von Human, Ratte und Maus. Er wurde validiert für ELISA, IHC, WB und IF.

Kurzübersicht für RAB3IP Antikörper (AA 230-310) (ABIN7219372)

Target: RAB3IP (RAB3A Interacting Protein (Rabin3) (RAB3IP))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB3IP Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-RAB3IP Antikörper

Bindungsspezifität: AA 230-310

Verwendungszweck: Rabbit Anti-RAB3IP Polyclonal Antibody

Spezifität: RAB3IP Polyclonal Antibody detects endogenous levels of RAB3IP protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human RAB3IP at AA range: 230-310

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu RAB3IP

Target: RAB3IP (RAB3A Interacting Protein (Rabin3) (RAB3IP))

Andere Bezeichnung: RAB3IP

Hintergrund: RAB3IP, RABIN8, Rab-3A-interacting protein, Rab3A-interacting protein, Rabin-3, SSX2-interacting proteinGuanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.

Molekulargewicht: 53kD

Gen-ID: 117177

UniProt: Q96QF0