RAB21 Antikörper (AA 60-140)

Produktnummer ABIN7230882

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RAB21 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für RAB21 Antikörper (AA 60-140) (ABIN7230882)

Target: RAB21 (RAB21, Member RAS Oncogene Family (RAB21))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RAB21 Antikörper

Bindungsspezifität: AA 60-140

Verwendungszweck: Rabbit Anti-RAB21 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of RAB21 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RAB21 protein at AA range: 60-140

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu RAB21

Target: RAB21 (RAB21, Member RAS Oncogene Family (RAB21))

Andere Bezeichnung: RAB21

Hintergrund: Ras-related protein Rab-21RAB21 (RAB21, Member RAS Oncogene Family) belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of RAB21 is associated with a poor prognosis for glioma patients. RAB21 is downregulated by the tumor suppressor miR-200b and miRNA-200b is itself downregulated in glioma tissues.

Molekulargewicht: 24kD

Gen-ID: 23011

UniProt: Q9UL25