RAB13 Antikörper (AA 40-120)

Produktnummer ABIN7230870

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RAB13 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für RAB13 Antikörper (AA 40-120) (ABIN7230870)

Target: RAB13 (RAB13, Member RAS Oncogene Family (RAB13))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RAB13 Antikörper

Bindungsspezifität: AA 40-120

Verwendungszweck: Rabbit Anti-RAB13 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of RAB13 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RAB13 protein at AA range: 40-120

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu RAB13

Target: RAB13 (RAB13, Member RAS Oncogene Family (RAB13))

Andere Bezeichnung: RAB13

Hintergrund: Ras-related protein Rab-13, Cell growth-inhibiting gene 4 proteinRAB13 (RAB13, Member RAS Oncogene Family) is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE). The encoded protein is involved in the assembly of tight junctions, which are components of the apical junctional complex (AJC) of epithelial cells. The AJC plays a role in forming a barrier between luminal contents and the underlying tissue. Additional functions associated with the protein include endocytic recycling of occludin, regulation of epithelial cell scattering, neuronal regeneration and regulation of neurite outgrowth. Alternately spliced transcript variants have been observed for RAB13. A pseudogene associated with RAB13 is located on chromosome 12.

Molekulargewicht: 22kD

Gen-ID: 5872

UniProt: P51153

Pathways: Cell-Cell Junction Organization