PWWP2B Antikörper (AA 240-320)

Produktnummer ABIN7220034

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PWWP2B in WB, ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für PWWP2B Antikörper (AA 240-320) (ABIN7220034)

Target: PWWP2B (PWWP Domain Containing 2B (PWWP2B))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PWWP2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-PWWP2B Antikörper

Bindungsspezifität: AA 240-320

Verwendungszweck: Rabbit Anti-PWWP2B Polyclonal Antibody

Spezifität: PWWP2B Polyclonal Antibody detects endogenous levels of PWWP2B protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human PWWP2B at AA range: 240-320

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PWWP2B

Target: PWWP2B (PWWP Domain Containing 2B (PWWP2B))

Andere Bezeichnung: PWWP2B

Hintergrund: PWWP2B, PWWP2, PWWP domain-containing protein 2BPWWP2B (PWWP domain containing 2B) is a 590 amino acid protein that contains a PWWP domain which is involved in protein-protein interactions. The PWWP2B protein is phosphorylated upon DNA damage, probably by Atm or ATR. The PWWP2B gene is conserved in chimpanzee, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 10q26. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4. % of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman's syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

Molekulargewicht: 64kD

Gen-ID: 170394

UniProt: Q6NUJ5