PROS1 Antikörper (AA 20-100)

Produktnummer ABIN7230792

Der Kaninchen Polyklonal anti-PROS1 Antikörper wird verwendet zum Nachweis von PROS1 in Proben von Human, Ratte und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für PROS1 Antikörper (AA 20-100) (ABIN7230792)

Target: PROS1 (PROS) (Protein S (PROS))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PROS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PROS1 Antikörper

Bindungsspezifität: AA 20-100

Verwendungszweck: Rabbit Anti-PROS Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of PROS protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PROS protein at AA range: 20-100

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PROS1

Target: PROS1 (PROS) (Protein S (PROS))

Andere Bezeichnung: PROS

Hintergrund: Vitamin K-dependent protein SPROS1 encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in PROS1 result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.

Molekulargewicht: 74kD

Gen-ID: 5627

UniProt: P07225