PRC1 Antikörper (pThr481)

Produktnummer ABIN7230766

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch PRC1 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PRC1 Antikörper (pThr481) (ABIN7230766)

Target: PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PRC1 Antikörper

Bindungsspezifität: pThr481

Verwendungszweck: PRC1 (Phospho-Thr481) Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of PRC1Phospho occurs at Thr481

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human PRC1 (Phospho-Thr481) Polyclonal Antibody protein at AA range: 481

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu PRC1

Target: PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

Andere Bezeichnung: PRC1

Hintergrund: Rabbit Anti-PRC1 (Phospho-Thr481) Polyclonal Antibody,Protein regulator of cytokinesis 1,PRC1 encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants. PRC1 (Protein Regulator Of Cytokinesis 1) is a Protein Coding gene. Among its related pathways are Semaphorin interactions and Cytoskeletal Signaling.,PRC1

Molekulargewicht: observerd band 72kDa

Gen-ID: 9055

UniProt: O43663