PPP1R16A Antikörper (AA 340-420)

Produktnummer ABIN7225488

Der Kaninchen Polyklonal anti-PPP1R16A Antikörper wird verwendet zum Nachweis von PPP1R16A in Proben von Human und Maus. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für PPP1R16A Antikörper (AA 340-420) (ABIN7225488)

Target: PPP1R16A (Protein Phosphatase 1, Regulatory Subunit 16A (PPP1R16A))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP1R16A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-PPP1R16A Antikörper

Bindungsspezifität: AA 340-420

Verwendungszweck: Rabbit Anti-MYPT3 Polyclonal Antibody

Spezifität: MYPT3 Polyclonal Antibody detects endogenous levels of MYPT3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human MYPT3 at AA range: 340-420

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IF/ICC1:50-200,ELISA 1:2000-20000,IHC 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PPP1R16A

Target: PPP1R16A (Protein Phosphatase 1, Regulatory Subunit 16A (PPP1R16A))

Andere Bezeichnung: MYPT3

Hintergrund: PPP1R16A, MYPT3, Protein phosphatase 1 regulatory subunit 16A, Myosin phosphatase-targeting subunit 3Myosin light chain kinase and phosphatase (MLCP) complexes control the phosphorylation states of regulatory myosin light chains, which is crucial for muscle and intracellular movement. MLCPs typically contain a catalytic protein phosphatase 1 (PP1c) subunit, a myosin phosphatase targeting (MYPT) subunit, and another smaller subunit. The protein encoded by MYPT3 (protein phosphatase 1 regulatory subunit 16A, PPP1R16A) represents an MYPT subunit, which is responsible for directing PP1c to its intended targets. However, while other MYPTs result in PP1c activation after becoming phosphorylated, the encoded protein is phosphorylated by protein kinase A and then inhibits the catalytic activity of PP1c.

Molekulargewicht: 60kD

Gen-ID: 84988

UniProt: Q96I34