Prohibitin 2 Antikörper

Produktnummer ABIN7230616

Der Kaninchen Polyklonal anti-Prohibitin 2 Antikörper (ABIN7230616) detektiert spezifisch Prohibitin 2 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Prohibitin 2 Antikörper (ABIN7230616)

Target: Prohibitin 2 (PHB2)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Prohibitin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Prohibitin 2 Antikörper

Verwendungszweck: Rabbit Anti-PHB2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of PHB2 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PHB2 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Prohibitin 2

Target: Prohibitin 2 (PHB2)

Andere Bezeichnung: PHB2

Hintergrund: B-cell receptor-associated protein BAP37, D-prohibitin, Repressor of estrogen receptor activityPHB2 (Prohibitin 2) is a Protein Coding gene. Diseases associated with PHB2 include Urethritis and Loiasis. Among its related pathways are GPCR Pathway and MAPK Signaling: mitogen Stimulation Pathway. GO annotations related to this gene include estrogen receptor binding. Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.

Molekulargewicht: 32kD

Gen-ID: 11331

UniProt: Q99623

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling