PAOX Antikörper (AA 260-340)

Produktnummer ABIN7217746

Dieser Anti-PAOX Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von PAOX in WB, ELISA und IHC (p). Geeignet für Human.

Kurzübersicht für PAOX Antikörper (AA 260-340) (ABIN7217746)

Target: PAOX (Polyamine Oxidase (Exo-N4-Amino) (PAOX))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAOX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PAOX Antikörper

Bindungsspezifität: AA 260-340

Verwendungszweck: PAOX Polyclonal Antibody

Spezifität: PAOX Polyclonal Antibody detects endogenous levels of PAOX protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human PAOX at AA range: 260-340

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu PAOX

Target: PAOX (Polyamine Oxidase (Exo-N4-Amino) (PAOX))

Andere Bezeichnung: PAOX

Hintergrund: Rabbit Anti-PAOX Polyclonal Antibody,PAOX, PAO, Peroxisomal N(1)-acetyl-spermine/spermidine oxidase, Polyamine oxidase,PAOX (Polyamine Oxidase (Exo-N4-Amino)) is a Protein Coding gene. Among its related pathways are Metabolism and cytochrome P450. Gene Ontology (GO) annotations related to this gene include receptor binding and polyamine oxidase activity. An important paralog of this gene is KDM1B. Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: n(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.,Peroxisomal N(1)-acetyl-spermine

Molekulargewicht: observerd band 70kDa

Gen-ID: 196743

UniProt: Q6QHF9