Poly(A) Binding Protein, Cytoplasmic, Pseudogene 2 (PABPCP2) (AA 170-250) Antikörper

Produktnummer ABIN7230470

Dieser Anti- Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von in WB und ELISA. Geeignet für Human und Maus.

Kurzübersicht für Poly(A) Binding Protein, Cytoplasmic, Pseudogene 2 (PABPCP2) (AA 170-250) Antikörper (ABIN7230470)

Target: Poly(A) Binding Protein, Cytoplasmic, Pseudogene 2 (PABPCP2)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails

Bindungsspezifität: AA 170-250

Verwendungszweck: PABP2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of PABP2 protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human PABP2 protein at AA range: 170-250

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Antigendetails

Target: Poly(A) Binding Protein, Cytoplasmic, Pseudogene 2 (PABPCP2)

Andere Bezeichnung: PABP2

Hintergrund: Rabbit Anti-PABP2 Polyclonal Antibody,Polyadenylate-binding protein 2, PABP-2, Poly(A)-binding protein 2, Nuclear poly(A)-binding protein 1, Poly(A)-binding protein II, PABII, Polyadenylate-binding nuclear protein 1,PABPN1 (Poly(A) Binding Protein Nuclear 1) encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. PABPN1 contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene.,PABP2

Molekulargewicht: observerd band 33kDa

Gen-ID: 8106

UniProt: Q86U42