Plastin 3 Antikörper (AA 180-260)
Kurzübersicht für Plastin 3 Antikörper (AA 180-260) (ABIN7230702)
Target
Alle Plastin 3 (PLS3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 180-260
-
Verwendungszweck
- PLS3 Polyclonal Antibody
-
Spezifität
- The antibody detects endogenous levels of PLS3 protein
-
Aufreinigung
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
-
Immunogen
- Synthesized peptide derived from part region of human PLS3 protein at AA range: 180-260
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
-
Kommentare
-
Primary Antibody
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- Plastin 3 (PLS3)
-
Andere Bezeichnung
- PLS3
-
Hintergrund
- Rabbit Anti-PLS3 Polyclonal Antibody,Phospholipid scramblase 3, PL scramblase 3, Ca(2+)-dependent phospholipid scramblase 3,May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.,PLS3
-
Molekulargewicht
- observerd band 32kDa
-
Gen-ID
- 57048
-
UniProt
- Q9NRY6
Target
-