PIM1 Antikörper (pTyr309)

Produktnummer ABIN7223146

Der Kaninchen Polyklonal anti-PIM1 Antikörper wird verwendet zum Nachweis von PIM1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für PIM1 Antikörper (pTyr309) (ABIN7223146)

Target: PIM1 (Pim-1 Oncogene (PIM1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PIM1 Antikörper

Bindungsspezifität: pTyr309

Verwendungszweck: Pim-1 (phospho Tyr309) Polyclonal Antibody

Spezifität: Phospho-Pim-1 (Y309) Polyclonal Antibody detects endogenous levels of Pim-1 protein only when phosphorylated at Y309.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Pim-1 Phospho-Tyr309

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu PIM1

Target: PIM1 (Pim-1 Oncogene (PIM1))

Andere Bezeichnung: Pim-1

Hintergrund: Rabbit Anti-Pim-1 (phospho Tyr309) Polyclonal Antibody,PIM1, Serine/threonine-protein kinase pim-1,The protein encoded by PIM1 (Pim-1 proto-oncogene, serine/threonine kinase) belongs to the Ser/Thr protein kinase family, and PIM subfamily. PIM1 is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons.,serine threonine-protein kinase pim-1

Molekulargewicht: observerd band 45kDa

Gen-ID: 5292

UniProt: P11309

Pathways: Glycosaminoglycan Metabolic Process