PDE4C Antikörper (AA 260-340)

Produktnummer ABIN7216476

Dieser Anti-PDE4C Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von PDE4C in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für PDE4C Antikörper (AA 260-340) (ABIN7216476)

Target: PDE4C (phosphodiesterase 4C, CAMP-Specific (PDE4C))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE4C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PDE4C Antikörper

Bindungsspezifität: AA 260-340

Verwendungszweck: PDE4C Polyclonal Antibody

Spezifität: PDE4C Polyclonal Antibody detects endogenous levels of PDE4C protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human PDE4C at AA range: 260-340

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu PDE4C

Target: PDE4C (phosphodiesterase 4C, CAMP-Specific (PDE4C))

Andere Bezeichnung: PDE4C

Hintergrund: Rabbit Anti-PDE4C Polyclonal Antibody,PDE4C, DPDE1, cAMP-specific 3', 5'-cyclic phosphodiesterase 4C, DPDE1, PDE21,Phosphodiesterase 4C encoded by PDE4C belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, phosphodiesterase 4C plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for PDE4C.,cAMP-specific 3',5'-cyclic phosphodiesterase 4C

Molekulargewicht: observerd band 80kDa

Gen-ID: 5143

UniProt: Q08493

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process