PDE4B/C/D Antikörper

Produktnummer ABIN7216474

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PDE4B/C/D in WB, IHC, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für PDE4B/C/D Antikörper (ABIN7216474)

Target: PDE4B/C/D (phosphodiesterase 4A/B/C, CAMP-Specific (PDE4B/C/D))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE4B/C/D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-PDE4B/C/D Antikörper

Verwendungszweck: Rabbit Anti-PDE4B/C/D Polyclonal Antibody

Spezifität: PDE4B/C/D Polyclonal Antibody detects endogenous levels of PDE4B/C/D protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human PDE4B/C/D around the non-phosphorylation site of S133/119/190

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PDE4B/C/D

Target: PDE4B/C/D (phosphodiesterase 4A/B/C, CAMP-Specific (PDE4B/C/D))

Andere Bezeichnung: PDE4B/C/D

Hintergrund: PDE4B, DPDE4, cAMP-specific 3', 5'-cyclic phosphodiesterase 4B, DPDE4, PDE32, PDE4C, DPDE1, cAMP-specific 3',5'-cyclic phosphodiesterase 4C, DPDE1, PDE21, PDE4D, DPDE3, cAMP-specific 3',5'-cyclic phosphodiesterase 4D, DPDE3, PDE43PDE4D encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. PDE4D uses different promoters to generate multiple alternatively spliced transcript variants that encode functiona.

Molekulargewicht: 76kD

Gen-ID: 5144, 5142, 5143

UniProt: Q07343, Q08493, Q08499