PDE10A Antikörper (AA 40-120)

Produktnummer ABIN7219164

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch PDE10A in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human und Ratte.

Kurzübersicht für PDE10A Antikörper (AA 40-120) (ABIN7219164)

Target: PDE10A (phosphodiesterase 10A (PDE10A))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE10A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PDE10A Antikörper

Bindungsspezifität: AA 40-120

Verwendungszweck: PDE10A Polyclonal Antibody

Spezifität: PDE10A Polyclonal Antibody detects endogenous levels of PDE10A protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human PDE10A at AA range: 40-120

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu PDE10A

Target: PDE10A (phosphodiesterase 10A (PDE10A))

Andere Bezeichnung: PDE10A

Hintergrund: Rabbit Anti-PDE10A Polyclonal Antibody,PDE10A, cAMP and cAMP-inhibited cGMP 3', 5'-cyclic phosphodiesterase 10A,The phosphodiesterase 10A encoded by PDE10A belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for PDE10A.,cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

Molekulargewicht: observerd band 75kDa

Gen-ID: 10846

UniProt: Q9Y233

Pathways: cAMP Metabolic Process