PIGC Antikörper (AA 170-250)

Produktnummer ABIN7230640

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PIGC in ELISA und WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für PIGC Antikörper (AA 170-250) (ABIN7230640)

Target: PIGC (Phosphatidylinositol Glycan C (PIGC))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIGC Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-PIGC Antikörper

Bindungsspezifität: AA 170-250

Verwendungszweck: Rabbit Anti-PIGC Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of PIGC protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PIGC protein at AA range: 170-250

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PIGC

Target: PIGC (Phosphatidylinositol Glycan C (PIGC))

Andere Bezeichnung: PIGC

Hintergrund: Phosphatidylinositol N-acetylglucosaminyltransferase subunit C, Phosphatidylinositol-glycan biosynthesis class C protein, PIG-CPIGC (Phosphatidylinositol Glycan Anchor Biosynthesis Class C) is a Protein Coding gene. Diseases associated with PIGC include Autosomal Recessive Non-Syndromic Intellectual Disability and Lassa Fever. Among its related pathways are Glycosylphosphatidylinositol (GPI)-anchor biosynthesis and Metabolism. PIGC encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI) lipid anchor biosynthesis. The GPI lipid anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. The encoded protein is one subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. Two alternatively spliced transcripts that encode the same protein have been found for PIGC. A pseudogene on chromosome 11 has also been characterized.

Molekulargewicht: 32kD

Gen-ID: 5279

UniProt: Q92535

Pathways: Inositol Metabolic Process