PGE Synthase Antikörper (Internal Region)

Produktnummer ABIN7216522

Der Kaninchen Polyklonal anti-PGE Synthase Antikörper (ABIN7216522) detektiert spezifisch PGE Synthase in ELISA, WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für PGE Synthase Antikörper (Internal Region) (ABIN7216522)

Target: PGE Synthase

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PGE Synthase Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PGE Synthase Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: Rabbit Anti-PGE synthase Polyclonal Antibody

Spezifität: PGE synthase Polyclonal Antibody detects endogenous levels of PGE synthase protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human PGE synthase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PGE Synthase

Target: PGE Synthase

Hintergrund: PTGES, MGST1L1, MPGES1, PGES, PIG12, Prostaglandin E synthase, Microsomal glutathione S-transferase 1-like 1, MGST1-L1, Microsomal prostaglandin E synthase 1, MPGES-1, p53-induced gene 12 proteinProstaglandin E synthase encoded by PTGES is a glutathione-dependent prostaglandin E synthase. The expression of PTGES has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that PTGES may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.

Molekulargewicht: 17kD

Gen-ID: 9536

UniProt: O14684