PEX5 Antikörper (AA 540-620)

Produktnummer ABIN7223872

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch PEX5 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für PEX5 Antikörper (AA 540-620) (ABIN7223872)

Target: PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PEX5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PEX5 Antikörper

Bindungsspezifität: AA 540-620

Verwendungszweck: Peroxin 5 Polyclonal Antibody

Spezifität: Peroxin 5 Polyclonal Antibody detects endogenous levels of Peroxin 5 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human Peroxin 5 at AA range: 540-620

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu PEX5

Target: PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))

Andere Bezeichnung: Peroxin 5

Hintergrund: Rabbit Anti-Peroxin 5 Polyclonal Antibody,PEX5, PXR1, Peroxisomal targeting signal 1 receptor, PTS1 receptor, PTS1R, PTS1-BP, Peroxin-5, Peroxisomal C-terminal targeting signal import receptor, Peroxisome receptor 1,The product of PEX5 (peroxisomal biogenesis factor 5) binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in PEX5 are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.,Peroxisomal targeting signal 1 receptor

Molekulargewicht: observerd band 70kDa

Gen-ID: 5830

UniProt: P50542

Pathways: Monocarboxylic Acid Catabolic Process