Peroxiredoxin 3 Antikörper (Internal Region)

Produktnummer ABIN7216668

Der Kaninchen-Polyklonal Anti-Peroxiredoxin 3-Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet zum Nachweis von Peroxiredoxin 3 in Proben aus Human, Ratte und Maus. }

Kurzübersicht für Peroxiredoxin 3 Antikörper (Internal Region) (ABIN7216668)

Target: Peroxiredoxin 3 (PRDX3)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Peroxiredoxin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Peroxiredoxin 3 Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: PRX III Polyclonal Antibody

Spezifität: PRX III Polyclonal Antibody detects endogenous levels of PRX III protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human PRX III

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Peroxiredoxin 3

Target: Peroxiredoxin 3 (PRDX3)

Andere Bezeichnung: PRX III

Hintergrund: Rabbit Anti-PRX III Polyclonal Antibody,PRDX3, AOP1, Thioredoxin-dependent peroxide reductase, mitochondrial, Antioxidant protein 1, AOP-1, HBC189, Peroxiredoxin III, Prx-III, Peroxiredoxin-3, Protein MER5 homolog,PRDX3 encodes a mitochondrial protein with antioxidant function. Peroxiredoxin 3 is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E.coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of PRDX3 results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22.,Thioredoxin-dependent peroxide reductase mitochondrial

Molekulargewicht: observerd band 26kDa

Gen-ID: 10935

UniProt: P30048

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process