Der Kaninchen Polyklonal anti-PER3 Antikörper (ABIN7225692) detektiert spezifisch PER3 in WB, ELISA, IHC und IF.
Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Haltbarkeit
12 months
Target
PER3
(Period Homolog 3 (PER3))
Andere Bezeichnung
Per3
Hintergrund
PER3, GIG13, Period circadian protein homolog 3, hPER3, Cell growth-inhibiting gene 13 protein, Circadian clock protein PERIOD 3PER3 (period circadian clock 3) is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. PER3 is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in PER3 have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for PER3.