PAX3 and PAX7 Binding Protein 1 (PAXBP1) Antikörper

Produktnummer ABIN7228626

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PAX3 and PAX7 Binding Protein 1 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für PAX3 and PAX7 Binding Protein 1 (PAXBP1) Antikörper (ABIN7228626)

Target: PAX3 and PAX7 Binding Protein 1 (PAXBP1)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails

Verwendungszweck: Rabbit Anti-GCFC1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of GCFC1 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human GCFC1 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Antigendetails

Target: PAX3 and PAX7 Binding Protein 1 (PAXBP1)

Andere Bezeichnung: GCFC1

Hintergrund: PAX3- and PAX7-binding protein 1, GC-rich sequence DNA-binding factor 1PAXBP1 encodes the PAX3 And PAX7 Binding Protein 1 that may bind to GC-rich DNA sequences, which suggests its involvement in the regulation of transcription. Alternative splicing of this gene results in multiple transcript variants. Adapter protein linking the transcription factors PAX3 and PAX7 to the histone methylation machinery and involved in myogenesis. Associates with a histone methyltransferase complex that specifically mediates dimethylation and trimethylation of Lys-4 of histone H3. Mediates the recruitment of that complex to the transcription factors PAX3 and PAX7 on chromatin to regulate the expression of genes involved in muscle progenitor cells proliferation including ID3 and CDC20 (By similarity).

Molekulargewicht: 100kD

Gen-ID: 94104

UniProt: Q9Y5B6