PTH1R Antikörper (AA 1268-1341)

Produktnummer ABIN7227082

Der Kaninchen Polyklonal anti-PTH1R Antikörper wird verwendet zum Nachweis von PTH1R in Proben von Human, Ratte und Maus. Er wurde validiert für WB, IHC, ELISA und IF.

Kurzübersicht für PTH1R Antikörper (AA 1268-1341) (ABIN7227082)

Target: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTH1R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-PTH1R Antikörper

Bindungsspezifität: AA 1268-1341

Verwendungszweck: Rabbit Anti-Parathyroid hormone/parathyroid hormone-related peptide receptor Polyclonal Antibody

Spezifität: The antibody detects endogenous Parathyroid hormone/parathyroid hormone-related peptide receptor.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic peptide from human protein at AA range: 1268-1341

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:500-200,ELISA 1:10000-20000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PTH1R

Target: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Andere Bezeichnung: Parathyroid hormone/parathyroid hormone-related peptide receptor

Hintergrund: Parathyroid hormone/parathyroid hormone-related peptide receptor, PTH/PTHrP type I receptor, PTH/PTHr receptor, Parathyroid hormone 1 receptor, PTH1 receptorThe protein encoded by PTH1R (parathyroid hormone 1 receptor) is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for PTH1R.

Molekulargewicht: 66kD

Gen-ID: 5745

UniProt: Q03431

Pathways: Regulation of Carbohydrate Metabolic Process