HRPT2 Antikörper (AA 51-100)

Produktnummer ABIN7230498

Der Kaninchen Polyklonal anti-HRPT2 Antikörper wird verwendet zum Nachweis von HRPT2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für HRPT2 Antikörper (AA 51-100) (ABIN7230498)

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HRPT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-HRPT2 Antikörper

Bindungsspezifität: AA 51-100

Verwendungszweck: Parafibromin Polyclonal Antibody

Spezifität: This antibody detects endogenous levels of Parafibromin

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human Parafibromin protein at AA range: 51-100

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu HRPT2

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Andere Bezeichnung: Parafibromin

Hintergrund: Rabbit Anti-Parafibromin Polyclonal Antibody,Parafibromin, Cell division cycle protein 73 homolog, Hyperparathyroidism 2 protein,CDC73 encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in CDC73 have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.,Parafibromin

Molekulargewicht: observerd band 60kDa

Gen-ID: 79577

UniProt: Q6P1J9

Pathways: Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance