PAKalpha/beta/gamma Antikörper (pSer139, pSer141, pSer144)

Produktnummer ABIN7222900

Der Kaninchen Polyklonal Anti-PAKalpha/beta/gamma Antikörper wurde für ELISA, WB und IHC (p) validiert. Er ist geeignet, PAKalpha/beta/gamma in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für PAKalpha/beta/gamma Antikörper (pSer139, pSer141, pSer144) (ABIN7222900)

Target: PAKalpha/beta/gamma

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAKalpha/beta/gamma Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PAKalpha/beta/gamma Antikörper

Bindungsspezifität: pSer139, pSer141, pSer144

Verwendungszweck: PAKα/β/γ (phospho Ser144/141/139) Polyclonal Antibody

Spezifität: Phospho-PAKα/β/γ (S144/141/139) Polyclonal Antibody detects endogenous levels of PAKα/β/γ protein only when phosphorylated at S144/141/139.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human PAKalpha/beta/gamma Phospho-Ser144/141/139

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu PAKalpha/beta/gamma

Target: PAKalpha/beta/gamma

Hintergrund: Rabbit Anti-PAKα/β/γ (phospho Ser144/141/139) Polyclonal Antibody,PAK1, Serine/threonine-protein kinase PAK 1, Alpha-PAK, p21-activated kinase 1, PAK-1, p65-PAK, PAK2, Serine/threonine-protein kinase PAK 2, Gamma-PAK, PAK65, S6/H4 kinase, p21-activated kinase 2, PAK-2, p58, PAK3, OPHN3, Serine/threonine-p,PAK1 encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,serine threonine-protein kinase PAK 1

Molekulargewicht: observerd band 65kDa

Gen-ID: 5058, 5062, 5063