PAK5/6 (pSer602) Antikörper

Produktnummer ABIN7223708

Dieser Anti-PAK5/6-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von PAK5/6 in WB und ELISA. Geeignet für Human und Maus.

Kurzübersicht für PAK5/6 (pSer602) Antikörper (ABIN7223708)

Target: PAK5/6

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails

Bindungsspezifität: pSer602

Verwendungszweck: PAK5/6 (phospho Ser602/S560) Polyclonal Antibody

Spezifität: Phospho-PAK5/6 (S602/S560) Polyclonal Antibody detects endogenous levels of PAK5/6 protein only when phosphorylated at S602/S560.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human PAK5/6 Phospho-Ser602/S560

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Antigendetails

Target: PAK5/6

Hintergrund: Rabbit Anti-PAK5/6 (phospho Ser602/S560) Polyclonal Antibody,PAK7, KIAA1264, PAK5, Serine/threonine-protein kinase PAK 7, p21-activated kinase 5, PAK-5, p21-activated kinase 7, PAK-7, PAK6, PAK5, Serine/threonine-protein kinase PAK 6, PAK-5, p21-activated kinase 6, PAK-6,The protein encoded by PAK5 (p21 (RAC1) activated kinase 5) is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.,serine threonine-protein kinase PAK 6

Molekulargewicht: observerd band 75kDa

Gen-ID: 57144, 56924