Paired Box 3 Antikörper (AA 150-230)

Produktnummer ABIN7230508

Der Kaninchen Polyklonal Anti-Paired Box 3 Antikörper wurde für WB und ELISA validiert. Er ist geeignet, Paired Box 3 in Proben von Human und Maus zu detektieren.

Kurzübersicht für Paired Box 3 Antikörper (AA 150-230) (ABIN7230508)

Target: Paired Box 3 (PAX3)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Paired Box 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Paired Box 3 Antikörper

Bindungsspezifität: AA 150-230

Verwendungszweck: PAX3 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of PAX3 protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human PAX3 protein at AA range: 150-230

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Paired Box 3

Target: Paired Box 3 (PAX3)

Andere Bezeichnung: PAX3

Hintergrund: Rabbit Anti-PAX3 Polyclonal Antibody,HuP2,PAX3 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.,PAX3

Molekulargewicht: observerd band 52kDa

Gen-ID: 5077

UniProt: P23760

Pathways: Sensory Perception of Sound, Tube Formation