Mu Opioid Receptor 1 Antikörper (AA 40-120)

Produktnummer ABIN7222870

Der Kaninchen Polyklonal Anti-Mu Opioid Receptor 1 Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, Mu Opioid Receptor 1 in Proben von Human zu detektieren.

Kurzübersicht für Mu Opioid Receptor 1 Antikörper (AA 40-120) (ABIN7222870)

Target: Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Mu Opioid Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Mu Opioid Receptor 1 Antikörper

Bindungsspezifität: AA 40-120

Verwendungszweck: MOR-1 Polyclonal Antibody

Spezifität: MOR-1 Polyclonal Antibody detects endogenous levels of MOR-1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human MOR-1 at AA range: 40-120

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Mu Opioid Receptor 1

Target: Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))

Andere Bezeichnung: MOR-1

Hintergrund: Rabbit Anti-MOR-1 Polyclonal Antibody,OPRM1, MOR1, Mu-type opioid receptor, M-OR-1, MOR-1, Mu opiate receptor, Mu opioid receptor, MOP, hMOP,OPRM1 encodes one of at least three opioid receptors in humans, the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503. : c. 18A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for OPRM1. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains.,Mu-type opioid receptor

Molekulargewicht: observerd band 48kDa

Gen-ID: 4988

UniProt: P35372

Pathways: cAMP Metabolic Process, Synaptic Membrane