OPRK1 Antikörper (AA 290-370)

Produktnummer ABIN7222868

Der Kaninchen Polyklonal Anti-OPRK1 Antikörper wurde für WB und ELISA validiert. Er ist geeignet, OPRK1 in Proben von Human, Ratte, Maus und Affe zu detektieren.

Kurzübersicht für OPRK1 Antikörper (AA 290-370) (ABIN7222868)

Target: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Reaktivität: Human, Ratte, Maus, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OPRK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-OPRK1 Antikörper

Bindungsspezifität: AA 290-370

Verwendungszweck: KOR-1 Polyclonal Antibody

Spezifität: KOR-1 Polyclonal Antibody detects endogenous levels of KOR-1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human KOR-1 at AA range: 290-370

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu OPRK1

Target: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Andere Bezeichnung: KOR-1

Hintergrund: Rabbit Anti-KOR-1 Polyclonal Antibody,OPRK1, OPRK, Kappa-type opioid receptor, K-OR-1, KOR-1,OPRK1 encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in OPRK1 have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.,Kappa-type opioid receptor

Molekulargewicht: observerd band 48kDa

Gen-ID: 4986

UniProt: P41145