Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch OPCML in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus und Affe.
OPCML
Reaktivität: Ratte
IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 680
Applikationshinweise
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
OPCML, IGLON1, OBCAM, Opioid-binding protein/cell adhesion molecule, OBCAM, OPCML, Opioid-binding cell adhesion molecule, IgLON family member 1OPCML encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily of proteins. Opioid binding protein/cell adhesion molecule like is proteolytically processed to generate the mature protein. Opioid binding protein/cell adhesion molecule like is localized in the plasma membrane and may have an accessory role in opioid receptor function. OPCML has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the opioid binding protein/cell adhesion molecule like is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.