OMG Antikörper (AA 260-340)

Produktnummer ABIN7216318

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch OMG in WB, ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für OMG Antikörper (AA 260-340) (ABIN7216318)

Target: OMG (Oligodendrocyte Myelin Glycoprotein (OMG))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OMG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-OMG Antikörper

Bindungsspezifität: AA 260-340

Verwendungszweck: Rabbit Anti-OMG Polyclonal Antibody

Spezifität: OMG Polyclonal Antibody detects endogenous levels of OMG protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human OMG at AA range: 260-340

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu OMG

Target: OMG (Oligodendrocyte Myelin Glycoprotein (OMG))

Andere Bezeichnung: OMG

Hintergrund: OMG, OMGP, Oligodendrocyte-myelin glycoproteinOligodendrocyte myelin glycoprotein (OMG, OMgp) is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes that influences the development of the adult central nervous system (CNS). OMG inhibits neurite outgrowth through its interaction with the Nogo receptor. This function requires its leucine-rich repeat domain, a highly-conserved region in OMG that influences cell proliferation, formation and maintenance of myelin sheaths. OMG inhibits neurite outgrowth from rat cerebellar granule and hippocampal cells, from dorsal root ganglion explants in which growth cone collapse was observed, from rat retinal ganglion neurons, and from NG108 and PC-12 cells.

Molekulargewicht: 48kD

Gen-ID: 4974

UniProt: P23515

Pathways: Neurotrophin Signalübertragung, Regulation of Cell Size